<i>In vivo</i> healing potential of <i>Vitis Vinifera</i> L. and <i>Punica Granatum</i> L. fruit extracts in excision and burn models in rabbits

Abstract Aim. The present study was carried out to evaluate the wound healing potential of crude Hydroalcoholic fruit extracts Grape ( Vitis vinifera L.) and Pomegranate Punica granatum in experimental animals. Material methods. Extracts were formulated as ointments (250 mg), their properties determined by using two models: i.e. excision burn models, rabbits. Wound assessed measuring rate contraction (percentage contraction) epithelialization period. Tukey test (HSD) used analyze obtained results. value p &lt;0.05 considered a level significance. reference standard wadded Cicatryl® ointment. Results. result showed that L. exhibited significant (p &lt;0.0001) (p&lt;0.0001) decrease period compared control (untreated) group both models studied. Conclusion. Our results suggest topical treatment accelerate activity, thus our supports traditional use. Both can be source therapeutics.